David M Jablons Selected Research

Radiotherapy

1/2024	Novel dual action PARP and microtubule polymerization inhibitor AMXI-5001 powerfully inhibits growth of esophageal carcinoma both alone and in combination with radiotherapy.
2/2020	Surgery for pleural mesothelioma, when it is indicated and why: arguments against surgery for malignant pleural mesothelioma.
9/2019	Case report: recurrent metastatic breast cancer in internal mammary dissection bed discovered at the time of coronary bypass.
11/2011	Implications of delayed initiation of radiotherapy: accelerated repopulation after induction chemotherapy for stage III non-small cell lung cancer.
10/2003	Intraoperative radiation therapy in the multimodality approach to upper aerodigestive tract cancer.
12/2002	Radical pleurectomy/decortication and intraoperative radiotherapy followed by conformal radiation with or without chemotherapy for malignant pleural mesothelioma.

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David M Jablons Research Topics

Disease

83	Neoplasms (Cancer) 01/2024 - 01/2003
30	Lung Neoplasms (Lung Cancer) 05/2021 - 01/2003
27	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2023 - 07/2002
24	Mesothelioma 02/2020 - 07/2002
17	Malignant Mesothelioma 01/2021 - 07/2002
16	Carcinogenesis 05/2020 - 08/2003
15	Neoplasm Metastasis (Metastasis) 05/2020 - 05/2005
6	Adenocarcinoma of Lung 12/2021 - 03/2006
5	Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar) 01/2013 - 03/2006
3	Sarcoma (Soft Tissue Sarcoma) 01/2019 - 05/2005
3	Adenocarcinoma 01/2016 - 01/2012
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2015 - 01/2012
2	Disease Progression 05/2023 - 06/2004
2	COVID-19 01/2023 - 06/2021
2	Carcinoid Tumor (Carcinoid) 09/2016 - 08/2014
2	Genomic Instability 05/2015 - 06/2014
2	Colorectal Neoplasms (Colorectal Cancer) 09/2007 - 04/2005
2	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 03/2007 - 12/2005
2	Malignant Pleural Effusion 03/2005 - 08/2003
1	Carcinoma (Carcinomatosis) 01/2024
1	Infections 06/2021
1	Wounds and Injuries (Trauma) 01/2021
1	Non-ST Elevated Myocardial Infarction 09/2019
1	Breast Neoplasms (Breast Cancer) 09/2019
1	Noninfiltrating Intraductal Carcinoma (DCIS) 09/2019
1	Coronary Artery Disease (Coronary Atherosclerosis) 09/2019

Drug/Important Bio-Agent (IBA)

26	Proteins (Proteins, Gene)FDA Link 05/2020 - 07/2002
16	Small Interfering RNA (siRNA)IBA 01/2019 - 01/2004
13	Biomarkers (Surrogate Marker)IBA 01/2023 - 01/2008
11	beta CateninIBA 09/2007 - 08/2003
6	Cullin Proteins (Cullins)IBA 01/2021 - 02/2011
6	LigandsIBA 07/2013 - 01/2004
5	AntibodiesIBA 01/2023 - 04/2003
5	Casein Kinase II (Casein Kinase 2)IBA 11/2013 - 05/2009
4	Carboplatin (JM8)FDA LinkGeneric 05/2023 - 06/2004
4	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 05/2003
3	Cisplatin (Platino)FDA LinkGeneric 01/2024 - 11/2007
3	Paclitaxel (Taxol)FDA LinkGeneric 05/2023 - 06/2004
3	Protein Isoforms (Isoforms)IBA 05/2021 - 08/2005
3	ErbB Receptors (EGF Receptor)IBA 08/2019 - 07/2007
3	B7-H1 AntigenIBA 08/2019 - 12/2017
3	Gemcitabine FDA Link 01/2016 - 11/2008
3	Messenger RNA (mRNA)IBA 11/2014 - 01/2012
3	SurvivinIBA 10/2008 - 07/2002
3	Secreted Frizzled-Related ProteinsIBA 09/2007 - 08/2004
3	Monoclonal AntibodiesIBA 05/2005 - 01/2004
3	WD repeat containing planar cell polarity effectorIBA 04/2005 - 08/2004
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2024 - 01/2020
2	Bevacizumab (Avastin)FDA Link 05/2023 - 06/2004
2	SulfatasesIBA 05/2021 - 01/2012
2	Phosphotransferases (Kinase)IBA 02/2021 - 08/2003
2	Verteporfin (Visudyne)FDA Link 01/2017 - 08/2016
2	Adenosine Triphosphate (ATP)IBA 01/2017 - 07/2013
2	Formaldehyde (Formol)FDA Link 01/2017 - 07/2016
2	ParaffinIBA 01/2017 - 07/2016
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 08/2016 - 01/2009
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2016 - 12/2015
2	hemateinIBA 11/2013 - 05/2009
2	Docetaxel (Taxotere)FDA Link 10/2013 - 04/2005
2	PlatinumIBA 11/2011 - 04/2010
2	Tyrosine Kinase InhibitorsIBA 01/2009 - 07/2007
2	Gefitinib (Iressa)FDA Link 01/2009 - 07/2006
2	Sirolimus (Rapamycin)FDA Link 11/2008 - 12/2005
2	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 11/2008 - 12/2005
2	Glycoproteins (Glycoprotein)IBA 01/2006 - 08/2005
1	Fluorouracil (Carac)FDA LinkGeneric 01/2024
1	Growth InhibitorsIBA 01/2024
1	talazoparibIBA 01/2024
1	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2024
1	niraparibIBA 01/2024
1	olaparibIBA 01/2024
1	rucaparibIBA 01/2024
1	RNA (Ribonucleic Acid)IBA 12/2021
1	TetraspaninsIBA 06/2021
1	ponatinibIBA 01/2021
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 05/2020
1	Growth Factor ReceptorsIBA 05/2020
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2020
1	Antineoplastic Agents (Antineoplastics)IBA 01/2020
1	Estrogen ReceptorsIBA 09/2019
1	Progesterone Receptors (Progesterone Receptor)IBA 09/2019
1	Immune Checkpoint InhibitorsIBA 08/2019
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 08/2019
1	TriterpenesIBA 08/2019

Therapy/Procedure

42	Therapeutics 01/2023 - 01/2003
18	Drug Therapy (Chemotherapy) 01/2024 - 12/2002
6	Radiotherapy 01/2024 - 12/2002
5	Adjuvant Chemotherapy 12/2021 - 01/2015
3	Immunotherapy 05/2020 - 01/2018
3	Pneumonectomy (Lung Volume Reduction) 02/2020 - 02/2007
3	Neoadjuvant Therapy 12/2016 - 04/2007
2	Metastasectomy 01/2019 - 04/2014
2	Esophagectomy 12/2016 - 01/2012
2	Precision Medicine 07/2016 - 01/2015
2	Investigational Therapies (Experimental Therapy) 07/2015 - 06/2014
2	Operative Surgical Procedures 04/2014 - 05/2009
2	Chemoradiotherapy 01/2009 - 04/2007
1	Oral Administration 01/2020
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 09/2019
1	Segmental Mastectomy (Lumpectomy) 09/2019